The Eisenberg Family Depression Center Leadership (DCL) team establishes priorities and strategic direction, advises on organizational, operational, programmatic, and development goals, and guides the initiation and achievement of integrative University of Michigan and extramural collaborative relationships. The DCL advances our interests and development by promoting and fostering the coordination and integration of activities with the Department of Psychiatry, in addition to other Health System and campus disciplines and advisory authorities across the institution.


Srijan Sen, M.D., Ph.D., Director, Eisenberg Family Depression Center, Frances and Kenneth Eisenberg Professor of Depression and Neurosciences, Professor of Psychiatry, University of Michigan's Associate Vice President for Research for the Health Sciences, Professor and Research Professor of Psychiatry and Molecular & Behavioral Neuroscience Institute

Srijan Sen is the Frances and Kenneth Eisenberg Professor of Depression and Neurosciences. Dr. Sen’s research focuses on the interactions between genes and the environment and their effect on stress, anxiety, and depression. He also has a particular interest in medical education, and leads a large multi-institution study that uses medical internship as a model of stress.

Standing Member

Gregory Dalack, M.D., Daniel E. Offutt III Professor and Chair, Department of Psychiatry

Gregory W. Dalack is the Daniel E. Offutt III Professor of Psychiatry and Chair of the Department of Psychiatry. He came to the University of Michigan in 1992 where he initially was Chief of the Mental Health Clinic at the VA Ann Arbor Healthcare System (VAAAHS). From 1999-2005, he was Chief of the Psychiatry Service at VAAAHS. In 2005, he became Associate Chair for Education and Academic Affairs (a position he still holds) for the department. From 2006-2007, he was Vice Chair of the department until assuming the role of Interim Chair in 2007.

Dr. Dalack has had research interests in the treatment of chronic and persistent mental illnesses, particularly focusing on schizophrenia. He has conducted studies examining nicotine addiction and smoking cessation interventions in schizophrenia, health behaviors in schizophrenia, and metabolic effects of second-generation antipsychotic medications in schizophrenia.

Dr. Dalack received his medical degree from the College of Physicians and Surgeons of Columbia University, completed his internship in Medicine at the Presbyterian Hospital in the City of New York and his Psychiatry Residency at the New York State Psychiatric Institute (NYSPI). Also at Columbia and NYSPI, he completed a fellowship in Psychopharmacology.

Associate Directors

Patricia Deldin, Ph.D., Associate Director Professor of Psychology, College of Literature, Science & the Arts Professor of Psychiatry

Patricia Deldin is a professor of Psychology and an associate professor of Psychiatry at the University of Michigan. Following a two year research position at the National Institute of Mental Health (NIMH), Dr. Deldin received her Ph.D. from the University of Illinois, with a major in clinical psychology and a minor in biological psychology. She then completed an internship at the University of Wisconsin, Madison, Department of Psychiatry. Dr. Deldin was on the faculty of Harvard University (1995-2003) before coming to the University of Michigan in 2003.

Dr. Deldin is one of the associate directors of the Eisenberg Family Depression Center and serves on the board of directors of the Society for Research in Psychopathology.

Her primary research program is comprised of information processing studies designed to distinguish memory, attention, and expectancy dysfunction in major depressives, dysthymics and controls. ERP, fMRI and behavioral studies provide complementary portraits of cognitive and emotional processing associated with depression.

Rosalind Garcia-Tosi, Sc.D, M.PH., M.S.W. Associate Director of Administration

Rosalind Garcia-Tosi joined the Depression Center in 2013 as the Associate Director of Administration. She holds “chief-of-staff” responsibilities for the Eisenberg Family Depression Center – she provides administrative oversight, coordinates inter-disciplinary initiatives, monitors and implements initiatives and projects and she also provides strategic planning support. Dr. Garcia-Tosi also functions as principal liaison for the Executive Director and other faculty leadership within and outside of the organization.

Prior to joining the Eisenberg Family Depression Center, Dr. Garcia-Tosi held various positions at a children’s health center, including Director of Child and Adolescent Psychiatry, Director of Strategic Planning and Evaluation, and Chair of the Institutional Review Board. She has worked for a public health policy research organization evaluating maternal and child health programs. Dr. Garcia-Tosi earned her Doctor of Science in Health Systems Management from Tulane University’s School of Public Health and Tropical Medicine and holds a Master’s in Public Health in Health Management & Policy and a Master of Social Work in Administration from the University of Michigan. She has extensive expertise in program evaluation, maternal and child health, mental health, management, strategic planning, collaboration, health equity, and health disparities. Dr. Garcia-Tosi co-teaches a Cultural Competency in Healthcare course at the University of Michigan-Flint.

John Greden, M.D., Rachel Upjohn Professor of Psychiatry and Clinical Neurosciences (Active Emeritus), Emeritus Research Professor, Molecular & Behavioral Neuroscience Institute, Founding Chair, National Network of Depression Centers, Chair Emeritus, Department of Psychiatry

Dr. John F. Greden is the Rachel Upjohn Professor of Psychiatry and Clinical Neurosciences, Founding Chair, National Network of Depression Centers (NNDC), and Research Professor, Emeritus, in the Michigan Neuroscience Institute at the University of Michigan. He earned his B.S. and M.D. at the University of Minnesota, completed his internship at Harbor/UCLA, and his psychiatry residency at the University of Minnesota Hospitals and Walter Reed Army Medical Center in Washington, DC. He previously served as Director of the Clinical Studies Unit for Affective Disorders and was Chair of Psychiatry at Michigan from 1985 until 2007.

Dr. Greden’s academic priorities have been the search for biomarkers of Major Depressive Disorders (MDD) and bipolar illnesses, aiming to develop and improve precision health approaches for these world-leading causes of disability. As Co-Director and then Director of the Clinical Studies Unit for Affective Disorders (CSU) at Michigan, he and his colleagues initially focused biomarker studies upon Hypothalamic-Pituitary-Adrenal (HPA) dysregulations, sleep electroencephalography, blood levels for antidepressant medications, and assessment of various biochemical, immune, and genetic risk variables. While Chair of Psychiatry at Michigan, he founded the Eisenberg Family Depression Center (www.depressioncenter.org) in 2001, the inaugural Center of its kind in the world, and the only Depression/Bipolar Center to date to receive funding support from NIH to aid facility construction. As Center Director, he developed and directed a Treatment Resistant Depression Clinic that sought to develop biomarkers for precise treatments. He aided introduction of evolving treatment strategies such as Transcranial Magnetic Stimulation, pharmacogenomic (PGx) assessments, ketamine trials, measurement-based care with mobile monitoring, and most recently seeks to employ artificial intelligence (AI) and machine learning to accelerate precision treatment approaches. His 2011 book on Treatment Resistant Depression: A Roadmap for Effective Care pointed out the pressing need for such precision treatments, emphasizing that “one size treatment will never fit all.”

Dr. Greden has had a 40-year history of grant funding, including two Center grants, more than 360 scientific publications, multiple books, and numerous invited/named lectureships. He has served as Past President of the Society of Biological Psychiatry, the Psychiatric Research Society, the American Association of Chairs of Departments of Psychiatry, and the American Foundation for Suicide Prevention. He was Co-Editor of the Journal of Psychiatric Research for 7 years and inaugural Chair of the Faculty Group Practice in the University of Michigan Health System. In 2006, he was Founding Chair of the National Network Depression Centers (www.NNDC.org), using a Foundation grant to integrate 16 major Universities to address the need for truly large-scale, longitudinal research projects to study major depression, bipolar illnesses and related disorders by adapting strategies used by the nation’s NCI cancer center network. The NNDC has grown to 27 major university members in the United States with international collaborators in Canada, Germany and India. Locally, he currently is a Gubernatorial appointment for the newly formed State of Michigan Suicide Prevention Commission and a consultant for Artificial Intelligence efforts to improve assessment of suicide risk. He is Project Director of the world’s largest pharmacogenomic study of those with difficult-to-treat depressions, aimed at developing guidelines for use of pharmacogenomic tests for treating depressions. His progressive contributions have been recognized by awards such as the Gerald L. Klerman Senior Investigator Award from the Depression and Bipolar Support Alliance (DBSA); the James T. Neubacher Award from the University of Michigan Council for Disability Concerns; the Gold Medal Award from the American Psychiatric Association for the Depression Center’s “Peer-to-Peer Program; the Crain’s Health Care Heroes Award; American College of Psychiatry Award for Mood Disorders Research; the American Psychiatric Association’s Mrazek Keynote Award in Pharmacogenomics; Fellowship in the American Association for Advancement of Science (AAAS); and most recently, the University of Michigan annual Board of Regents Award for Distinguished Public Service. He has a commitment to using research evidence to shape policy, practice and funding by develop a new generation of translational scholars, presenting ten keynote addresses for the American Psychiatric Association’s “Psychiatry Young Investigators Colloquium” and proudly noting that nine former psychiatry residents that he helped mentor at Michigan are now Chairs of Psychiatry in U.S. Medical Schools. Dr. Greden also speaks widely for community organizations, presenting to nearly 50 media outlets in the past years; writing numerous op-eds and articles and giving dozens of presentations tailored to the general public.

Amy M. Kilbourne, Ph.D., M.PH., Director, Quality Enhancement Research Initiative (QUERI), U.S. Dept. of Veteran Affairs, Professor and Associate Chair for Research, Learning Health Sciences, Professor of Psychiatry

Dr. Kilbourne is Professor of Psychiatry at the University of Michigan and is Director of the Quality Enhancement Research Initiative (QUERI) national program, U.S. Dept. of Veterans Affairs. Dr. Kilbourne is a national expert in collaborative care models for mood disorders and implementation science, including the design of implementation strategies (Enhanced Replicating Effective Programs) to promote the more rapid translation of research findings into actionable policy and practice. She also co-directs the UM Psychiatry Integrated Care Medicaid Match Program, which is focused on implementing and evaluating programs to improve physical and behavioral health services for Michigan residents.

Dr. Kilbourne has been widely recognized for her development of integrated treatment models for depression and bipolar disorders (Life Goals), cardiovascular risk reduction in mood disorders, measurement-based care, healthcare analytics, and health policy. Her research has led to several national improvement initiatives and policies across large healthcare systems, including a VA national population management program for persons with schizophrenia or bipolar disorders, a health disparities research roadmap, and a psychosocial intervention toolkit to improve physical and behavioral health outcomes for persons with mood disorders.

Dr. Kilbourne is the recipient of several awards including the prestigious Presidential Early Career Award for Scientists and Engineers (PECASE) and the Gerald L. Klerman Research Award from the Depression and Bipolar Support Alliance (DBSA). Dr. Kilbourne also serves on several national committees, including the Agency for Healthcare Research and Quality (AHRQ) DEcIDE Network for comparative effectiveness and patient-centered outcomes research, the National Institutes of Health (NIH) mental health services study section, and is a Senior Fellow with the Partnership for Public Service in Washington D.C. Dr. Kilbourne received her bachelors of arts at the University of California at Berkeley (double major in molecular biology and rhetoric), and her masters in epidemiology and PhD in health policy and administration from the University of California Los Angeles.

Melvin McInnis, M.D., FRCPsych, Associate Director, Thomas B. and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression, Department of Psychiatry Director of Prechter Bipolar Research Program

Melvin G. McInnis, M.D., the Thomas B. and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression, leads the University of Michigan’s clinical treatment and research group for Bipolar Disorder. Dr. McInnis, received his medical training at the University of Iceland, where he developed his interest in the genetics of bipolar disorder. He completed a psychiatric residency at the Bethlem Royal and Maudsley Hospitals at the University of London and then spent 15 years at Johns Hopkins University, where he became an associate professor and director of the George Brown Genetics Laboratory. Dr. McInnis has published more than 100 peer-reviewed articles on the genetics and clinical course of bipolar disorders. He is known as an expert in the diagnosis, genetics and clinical management of bipolar and depressive disorders in adolescents and adults.

Sagar V. Parikh, M.D., FRCPC, Associate Director John F. Greden Professor of Depression and Clinical Neuroscience Professor of Psychiatry

In March 2015, Dr. Sagar Parikh was appointed as the John F. Greden Professor of Depression and Clinical Neuroscience, and Professor of Psychiatry, at the University of Michigan, Ann Arbor, where he was also designated Associate Director of the Eisenberg Family Depression Center. Dr. Parikh is also Professor of Psychiatry at the University of Toronto, where he was on staff full-time from 1994-2015. In Toronto, he served as Director of Continuing Mental Health Education and Head of General Psychiatry, and at Toronto’s major hospital grouping, the University Health Network, he completed two terms as Deputy Psychiatrist-in-Chief and served as President of the Medical Staff Association and as a member of the Board of Trustees. Previously, he was head of the Bipolar Clinic and Director of CME at the Centre for Addiction and Mental Health (CAMH) in Toronto.

Dr. Parikh is the author / editor of two books and over 130 peer-reviewed articles and book chapters, and co-author of CANMAT treatment guidelines for Depression and for Bipolar Disorder, the world’s most cited mood disorder guidelines. He holds research grants from multiple funding agencies, covering studies in clinical treatments in mood disorders, health services research, genetics, epidemiology, and educational research. He has conducted clinical trials looking at the combination of medication and psychotherapy for bipolar disorder and for depression, as well as pharmacotherapy trials in mood disorders. Current major projects include a multi-site study of Biomarkers in Major Depression, Anti-Stigma interventions in Bipolar disorder, Workplace Depression interventions, and a RCT of Telephone-Delivered CBT for Bariatric Surgery patients. As medical director of Mensante, he helped create a novel internet system for recognition and management of mental disorders that is commercially marketed.

Dr. Parikh has a special interest in Continuing Education and Knowledge Translation research and delivery, having developed and tested novel CME programs to teach clinicians new skills to diagnose and treat mood disorders. He published a new theoretical model on how physicians learn and change practice behaviour in stages, and developed new toolkits and Knowledge Translation products as part of larger plan for treatment guideline dissemination. These interventions address multiple determinants of health by using multiple strategies—medication, psychotherapy, biomarkers, education—directed towards multiple targets, namely patients, providers, and systems.

Dr. Parikh was awarded the Dave Davis CEPD Research Award from the University of Toronto in 2008 and the R.O. Jones Award for Best Research Paper by the Canadian Psychiatric Association in 2011. He serves as Secretary of the International Society for Affective Disorders, and Co-Head, Section of Affective Disorders, World Psychiatric Association. He was honored by the Canadian Psychiatric Association by delivering the Distinguished Member Lecture at the 2007 CPA Annual Meeting. His teaching has won him three local, two national, and one international awards, most recently the Association of Chairs of Psychiatry Award for Excellence in Education.

Dr. Parikh’s education spans both the US and Canada, as a graduate of Phillips Academy, Andover; Columbia University (Bachelor of Science in Bioengineering); and McGill University Faculty of Medicine (M.D, C.M.).

He trained in Psychiatry at the University of Michigan, Ann Arbor and at the University of Toronto, and subsequently completed a two-year Research and Clinical Fellowship at the University of Toronto.

Michelle Riba, M.D., M.S., Associate Director, Professor of Psychiatry, Director, PsychOncology Program, U-M Rogel Cancer Center, Past President, American Psychiatric Association

Dr. Riba is Clinical Professor and Associate Chair for Integrated Medical and Psychiatric Services in the Department of Psychiatry, Associate Director of the University of Michigan Comprehensive Depression Center, and Director of the PsychOncology Program at the University of Michigan Comprehensive Cancer Center.

Dr. Riba’s clinical and research interests as a psychosomatic medicine psychiatrist include primary care psychiatry, depression and cardiovascular disease, depression and cancer, and the role of screening for distress in patients with cancer/medical illness. Dr. Riba is a Zonal Representative for the World Psychiatric Association and Past-President of the American Psychiatric Association, the Association for Academic Psychiatry, and the American Association of Directors of Psychiatric Residency Training.

As director of the University of Michigan Comprehensive Cancer Center PsychOncology Program, Dr. Riba leads a multidisciplinary group of clinicians who care for the emotional needs of cancer patients and their families; including physicians, nurses, social workers, art therapists, child life specialists and psychologists. Through numerous scientific papers, APA courses, books, and presentations at scientific meetings, she continues to advance the dialogue and research in this important clinical area nationally and internationally.

Dr. Riba is the author or editor of over 100 scientific articles, books, chapters and scientific abstracts. She has served on the editorial board of Psychiatric Services and Cancer News on the Net, Current Psychiatry and has served on the editorial advisory board of the American Psychiatric Press, Inc. She is a reviewer for Psycho-Oncology; Academic Psychiatry; Psychiatric Services; Journal of Psychiatric Practice; and Psychosomatic Medicine; Breast Cancer Research and Treatment. She has co-edited 15 editions of The American Psychiatric Press Review of Psychiatry series. She has co-edited Psychopharmacology and Psychotherapy: A Collaborative Approach; Primary Care Psychiatry; and The Doctor-Patient Relationship in Pharmacotherapy: Improving Treatment Effectiveness and has edited or co-written another 15 books.

Ex Officio Members

Gloria Harrington, MBA, LMSW, CCRP, Chief Department Administrator & Eisenberg Family Depression Center Administrator, and Research Operations Manager at the U-M Department of Psychiatry

Gloria Harrington's primary focus for the department has involved guidance on research policy and compliance, strategy development, and infrastructure support for faculty and their teams. She serves as an informal mentor for both faculty and staff around HR, IRB, and general project support.

Gloria received her Master of Social work from Wayne State University, a Master of Business Administration from Cleary University, and has been a Certified Clinical Research Professional from SoCRA since 2012.