Sequenced Treatment Alternatives to Relieve Depression
The University of Michigan STAR*D center, directed by Elizabeth Young, M.D., is one of 14 STAR*D regional centers. The purpose of the STAR*D Study is to determine the effectiveness of different treatments for people with Major Depressive Disorder (MDD) who have not responded to initial treatment with an antidepressant. This is the largest and longest study ever done to evaluate depression treatment. Over a seven-year period, the study enrolled more than 4,000 outpatients, aged 18-75 years. The participants were people who came to their doctors for care and who had other psychiatric and medical conditions like those regularly seen in typical clinical practices. Patients from both mental health (specialty care) and non-mental health (primary medical care) practices in diverse racial, ethnic, and socioeconomic populations were enrolled in the study.
STAR*D in the News:
- Pushing Boundaries Medicine at Michigan
- New Strategies Help Depressed Patients Become Symptom-Free NIMH
- Remissions in Maternal Depression and Child Psychopathology JAMA
- Study: Patients shouldn't give up on banishing depression USA Today
- Medication Augmentation after the Failure of SSRIs for Depression NEJM
