Participate in Sleep Research

We need volunteers to be involved in our research examining the relationship between depressive disorders and sleep. We have a strong interest in the biological risk factors for depression and how a major depressive disorder can affect the sleep of both children and adults. Insomnia and biological rhythm problems are also a focus of our clinical service and research program.

Most of our studies require a minimum of two overnight sleep studies.

General Eligibility Requirements for Research Participation

• Generally medically healthy
• Ability to participate in psychiatric evaluation (approximately 1-2 hours)
• Ability to spend 1-4 consecutive nights in the Sleep Lab (varies with study)

Studies currently seeking participants:

Adolescent Sleep Delay Study (HUM00019045)
Purpose: This study looks at differences in how the brain responds to changes in sleep schedules in teens who are depressed and teens with no history of a mental health disorder.
Eligibility: Males, ages 13-18, either currently depressed or with no history of mental health disorder and no first degree family history of mental health disorder. Must be physically mature, in good physical health and sleep between 7-10 hours a night.

Targeting Sleep to Improve Medication Response in Depression (HUM00023276)
Purpose: Medications used to treat depression can take up to 6-8 weeks to begin working effectively and may not provide adequate relief from depression symptoms. This study explores whether manipulating sleep in combination with an FDA-approved depression medication is a safe and more effective treatment for depression.
Eligibility: 18-65 years old; currently depressed but not taking mood medications; otherwise generally healthy; sleeping 7-10 hours a night.

Call the Mental Health Research line at (734) 232-0255, or visit www.UMClinicalStudies.org to learn more about these and other opportunities to participate in sleep research.